Treatment & Medication

A neurologist explains who Botox for migraine actually helps, why it fails for some people, and what to try next — even if you don’t qualify.

Aimovig, Ajovy, or Emgality not helping your migraines? A neurologist explains the real reasons CGRP shots fail — and the next moves that actually work.

Sumatriptan failing doesn’t mean you’re out of options. A headache neurologist on the four real reasons triptans stop working — and what actually comes next.

Gepants are oral small-molecule CGRP receptor antagonists used for both acute and preventive migraine therapy. A neurologist summarizes the mechanism, indications, and NEJM/Lancet evidence for rimegepant, ubrogepant, and atogepant, plus differences from triptans and CGRP antibodies.

Headache patterns during pregnancy change due to hormonal, hemodynamic, and sleep shifts. A neurologist summarizes trimester-by-trimester safety of acetaminophen, NSAIDs, triptans; differentiation of preeclampsia, CVST, and RCVS; and medications safe to use during lactation per ACOG/AHS guidance.

Emgality and Ajovy are CGRP antibody injections that prevent migraines rather than just treat them. A neurologist explains how they work, their efficacy, and how to choose between them.

GLP-1 injections (Wegovy, Mounjaro) can both relieve and worsen migraines. Explained through brain energy metabolism.

CGRP antibody 5-year safety data, new gepants, magnesium meta-analysis, updated AHS guidelines, and digital therapeutics — the essential 2026 updates.

Acute vs preventive headache medications explained by a 25-year specialist.